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Description
Amyloid Precursor Protein Recombinant Rabbit mAb (S-806-13)Product Specification Host Rabbit Synonyms APP, ABPP, APPI, Alzheimer disease amyloid A4 protein homolog, Alzheimer disease amyloid protein, Amyloid beta precursor protein, Amyloid beta (A4) precursor protein, Amyloid beta A4 protein, Cerebral vascular amyloid peptide (CVAP), PreA4, Protease nexin II (PN II) Immunogen Synthetic Peptide Location Cell membrane Accession P05067 Clone Number S 806 13 Antibody Type Recombinant mAb Isotype IgG Application
Product Specification
| Host | Rabbit |
| Synonyms | APP, ABPP, APPI, Alzheimer disease amyloid A4 protein homolog, Alzheimer disease amyloid protein, Amyloid-beta precursor protein, Amyloid-beta (A4) precursor protein, Amyloid-beta A4 protein, Cerebral vascular amyloid peptide (CVAP), PreA4, Protease nexin-II (PN-II) |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P05067 |
| Clone Number | S-806-13 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, ICFCM |
| Reactivity | Hu |
| Predicted Reactivity | Fs, Pg, Ms, Rt, Mq, Cz, GP, Pr |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:100 | |
| ICC | 1:100 | |
| ICFCM | 1:500 |
Background
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions as a cell surface receptor and has been implicated as a regulator of synapse formation, neural plasticity, antimicrobial activity, and iron export. APP is best known as the precursor molecule whose proteolysis generates amyloid beta (Aβ), a polypeptide containing 37 to 49 amino acid residues, whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.
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Exchange/Return Notes
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4.7 ★★★★★
Based on 2481 reviews
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Product Reviews
★★★★★ 5
Total GAME CHANGER - incredibly effective toothbrush for dogs
Color: Clear (2-pack)
This silicon finger brush is incredibly easy to use - and so EFFECTIVE (more on that in the last paragraph this review). At first, it seemed a little hard to get on my finger but I simply got my finger wet first under the faucet and it slipped right on with virtually no effort. And once on, it's easy to take off but doesn't slip off accidentally when in use - so - perfect! Quick & simply to clean - rinses off in the sink in seconds, and ready to use the next time. And, my dog not only lets me clean her teeth - she actually like it (this from a dog who used to hate it when I would try to brush her teeth with a regular doggy toothbrush).
This silicon "brush" is incredibly maneuverable - way more so than standard dog toothbrushes or regular finger brushes. So much so it makes it super easy to not only get those normally impossible to reach back molars - AND - even the back sides of the teeth! With a normal dog tooth brush (or finger brush) my dog's clamping down made that impossible. Now, it's not only possible - it's easy!
Our dog's canine teeth had build-up but it was not until I pulled her gums back and looked at her back molars that I saw how bad things had gotten - and we have a young dog! Her back molars not only had build-up but some appeared to be stained a tea colored brown that did not come off with my fingernail. It was pretty disheartening and I felt terrible. How could this happen so quickly? The vet said it was plaque (and not yet tartar) and that it wasn't bad enough to warrant a professional cleaning - yet - but that I needed to do a better job brushing. He said: "I can see exactly where your brushing stops" (referring to the condition on the back molars which I had not been able to do with a regular brush as my dog just wasn't having it).
Tips: here's what's working for us. Instead of squeezing out a pea sized blog of tooth paste onto this brush, I put a tiny dab - that it's - on the very tip of the brush and focus my efforts on two of our dog's worst teeth on one side - on top and then on the bottom. Then I put another small dab and repeat on the other side of her mouth with 4 teeth on that side. Then, I use another small dab and focus work on another group of teeth. All totaled, I'm using maybe 4 to 6 very small dabs of dog toothpaste, probably half the size of pea collectively, perhaps less. That's it. However much you choose to use is up to you - be sure and use an amount that's safe and effective for your dog.
Effectiveness: this works and it works well! In just 3 days using the same vanilla flavored enzymatic toothpaste by CET I was seeing improvement. By day 7, that improvement was so obvious I was actually surprised by how much better they looked. It's now been a little over two weeks and they are looking considerably better! Conservatively, I'm thinking a 50% improvement. Not bad for just 2 weeks, right? I'm actually think I'm going to be able to completely reverse things - we'll see. I'll try and update this review again in a few weeks and let you know how it's looking but in the meantime, I am absolutely thrilled with this brush. I paid $16 and it came 2 in a pack) and the first (and only one) I've been using still looks brand new after it's rinsed off. All in all - this brush is a game changer! I can now brush our dogs back teeth and even the back sides of her teeth, all in less than a couple minutes a day.
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Reviewed in the United States on August 23, 2020
★★★★★ 3
Plastic not a brush
Color: Clear (4-pack)
Love the idea, dont care for the texture. It would be nice if they were soft brush and not plastic.
Would retuen but i missed the window.
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Reviewed in the United States on May 22, 2026
★★★★★ 5
Better than a toothbrush!
Color: Blue (2-pack)
Perfect for brushing my doggies teeth!
Easy to use and my dogs like it better than a toothbrush.
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Reviewed in the United States on June 2, 2026
★★★★★ 5
Great dog toothbrush!
Color: Blue (2-pack)
I’ve been using this product for a year now, and it’s been working great. When paired with vanilla mint enzymatic toothpaste, it effectively cleans my Pomsky’s teeth, including the back teeth. As a result, my fur baby’s teeth remain as white as ever!
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Reviewed in the United States on May 27, 2026
★★★★★ 5
great for Odor control and also seems to be calming to the cats.
This product is magic. for my cats it not only smells good and don't need more than 1 spray pump, but it also acts to sooth the cats , creating a calmness in them somehow. I will definitely buy more as this begins to run low, love this product. Works fantastic for odor control and seems like it is not just masking. highly recommend this product!
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Reviewed in the United States on February 5, 2026
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